TP0136 anti-syphilis antibodies in development are poorly understood. This study aimed to determine the effect of anti-TP0136 antibodies on lesion development in infected rabbit models. rTP0136 intramuscular injection into rabbits in the immunized group (n = 4) induce high titers of anti TP0136-antibody, and rabbit then challenged with 105T. pallidum per site along their back. lesion development was observed, and the injection sites were biopsied for tp0574 mRNA and histological analysis every week until the wound is healed. Rabbits in the control group were injected with normal saline instead rTP0136. Decent T. pallidum in rabbits challenged assessed by a test rabbit infectivity.
Lesions in the immunized group took longer to heal than in the control group (42 d vs 28 d, P <0.001) and had a real level higher than the number of cellular infiltrates. MRNA levels of tp0574 the immunized group was significantly higher than in the control group (P <0.05). Decent T. pallidum detected in the lymph nodes of rabbits in both groups were immunized and control. Our study shows that a high titer antibody anti TP0136-promoted infiltration of inflammatory cells into the local lesions and tissue damage intensive, thereby delaying wound healing, and does not have a protective effect on the occurrence of syphilis in a rabbit model.
Kinesis See Part Number P-332 - PK10 |
|||
CHR4033 | Scientific Laboratory Supplies | PK10 | EUR 22.38 |
piggyBac qPCR copy number kit, 20 reactions |
|||
PBC100A-1 | SBI | 20 reactions | EUR 275 |
copy number positive control for custom assay |
|||
Z-any-std | Novacyt Group | each | EUR 198 |
Drain Tap Assembly to suit baths with serial number: 75100 - EACH |
|||
BAT7360 | Scientific Laboratory Supplies | EACH | EUR 89.1 |
copy number positive control for custom rat assay |
|||
Z-ra-std | Novacyt Group | each | EUR 198 |
Description: Control |
copy number positive control for custom mouse assay |
|||
Z-mo-std | Novacyt Group | each | EUR 198 |
copy number positive control for custom human assay |
|||
Z-hu-std | Novacyt Group | each | EUR 217 |
Description: Control |
Kinesis Septa TCS 11mm Bought as part number without /S - EACH |
|||
CHR1750 | Scientific Laboratory Supplies | EACH | EUR 4.8 |
Kinesis Obsolete see part number M-653 Headless; 10-32; 1/16 |
|||
CHR3683 | Scientific Laboratory Supplies | PK10 | EUR 50.16 |
Trametinib, DMSO Solvate [CAS# 1187431-43-1] |
|||
T-8188 | LC LABORATORIES | 10 mg | EUR 38 |
DMSO |
|||
40470004-1 | Glycomatrix | 500 mL | EUR 69.23 |
DMSO |
|||
40470004-2 | Glycomatrix | 1 L | EUR 107.61 |
DMSO |
|||
40470004-3 | Glycomatrix | 100 mL | EUR 34.04 |
DMSO |
|||
40470004-4 | Glycomatrix | 250 mL | EUR 41.19 |
DMSO |
|||
40470004-5 | Glycomatrix | 50 mL | EUR 22.74 |
DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7* |
|||
17575 | AAT Bioquest | 0.2 ml | EUR 227 |
Description: DiTO™-1 is chemically equivalent to TOTO®-1 (TOTO® is the trademark of Invitrogen). |
DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7* |
|||
17575-02ml | AAT Bioquest | 0.2 ml | EUR 222 |
Description: DiTO™-1 is chemically equivalent to TOTO®-1 (TOTO® is the trademark of Invitrogen). |
DiYO™-3 [equivalent to YOYO®-3] *5 mM DMSO Solution* *CAS 156312-20-8* |
|||
17581 | AAT Bioquest | 0.2 ml | EUR 227 |
Description: DiYO™-3 is chemically equivalent to YOYO®-3 (YOYO® is the trademark of Invitrogen). |
DiYO™-3 [equivalent to YOYO®-3] *5 mM DMSO Solution* *CAS 156312-20-8* |
|||
17581-02ml | AAT Bioquest | 0.2 ml | EUR 222 |
Description: DiYO™-3 is chemically equivalent to YOYO®-3 (YOYO® is the trademark of Invitrogen). |
DMSO, anhydrous |
|||
90082-1 | Biotium | EA | EUR 31 |
Dimethylsulfoxide (DMSO), 500ml |
|||
PC0906-500ml | Vivantis | each | Ask for price |
Dry DMSO, 2ML |
|||
X022-2ML | Arbor Assays | 2ML | EUR 37 |
Dry DMSO, 4ML |
|||
X022-4ML | Arbor Assays | 4ML | EUR 54 |
Dry DMSO, 5ML |
|||
X022-5ML | Arbor Assays | 5ML | EUR 59 |
Dry DMSO, 14ML |
|||
X022-14ML | Arbor Assays | 14ML | EUR 109 |
Dry DMSO, 20ML |
|||
X022-20ML | Arbor Assays | 20ML | EUR 168 |
MAGNETIC NUMBERS WHITE 18/23MM AB Labels |
|||
224065 | BRADY NV | Vel of 257 Label(s) | EUR 41.64 |
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille |
MAGNETIC NUMBERS WHITE 39/43MM AB Labels |
|||
224066 | BRADY NV | Vel of 85 Label(s) | EUR 45.2 |
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille |
MAGNETIC NUMBERS YELLOW 18/23MM AB Labels |
|||
224063 | BRADY NV | Vel of 257 Label(s) | EUR 41.64 |
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille |
MAGNETIC NUMBERS YELLOW 39/43MM AB Labels |
|||
224064 | BRADY NV | Vel of 85 Label(s) | EUR 45.2 |
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille |
TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2* |
|||
17571 | AAT Bioquest | 0.2 ml | EUR 227 |
Description: TWO-PRO™-1 is chemically equivalent to TO-PRO®-1 (TO-PRO® is the trademark of Invitrogen). |
TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2* |
|||
17571-02ml | AAT Bioquest | 0.2 ml | EUR 222 |
Description: TWO-PRO™-1 is chemically equivalent to TO-PRO®-1 (TO-PRO® is the trademark of Invitrogen). |
TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8* |
|||
17572 | AAT Bioquest | 0.2 ml | EUR 227 |
Description: TWO-PRO™-3 is chemically equivalent to TO-PRO®-3 (TO-PRO® is the trademark of Invitrogen). |
TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8* |
|||
17572-02ml | AAT Bioquest | 0.2 ml | EUR 222 |
Description: TWO-PRO™-3 is chemically equivalent to TO-PRO®-3 (TO-PRO® is the trademark of Invitrogen). |
Trametinib DMSO solvate |
|||
123211 | MedKoo Biosciences | 10.0mg | EUR 90 |
Dimethyl sulfoxide (DMSO) |
|||
D0231 | Bio Basic | 500ml | EUR 88.55 |
Trametinib DMSO solvate |
|||
A3887-10 | ApexBio | 10 mg | EUR 40 |
Description: Allosteric MEK1/MEK2 kinase inhibitor |
Trametinib DMSO solvate |
|||
A3887-100 | ApexBio | 100 mg | EUR 95 |
Description: Allosteric MEK1/MEK2 kinase inhibitor |
Trametinib DMSO solvate |
|||
A3887-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 44 |
Description: Allosteric MEK1/MEK2 kinase inhibitor |
Trametinib DMSO solvate |
|||
A3887-50 | ApexBio | 50 mg | EUR 64 |
Description: Allosteric MEK1/MEK2 kinase inhibitor |
Trametinib (DMSO solvate) |
|||
HY-10999A | MedChemExpress | 100mg | EUR 256.8 |
Trametinib (DMSO Solvate) |
|||
T314310 | Toronto Research Chemicals | 100mg | EUR 800 |
Description: 1187431-43-1 |
Trametinib (DMSO solvate) |
|||
T5857-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Trametinib (DMSO solvate) |
Trametinib (DMSO solvate) |
|||
T5857-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Trametinib (DMSO solvate) |
Trametinib (DMSO solvate) |
|||
T5857-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Trametinib (DMSO solvate) |
Trametinib (DMSO solvate) |
|||
T5857-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Trametinib (DMSO solvate) |
Trametinib (DMSO solvate) |
|||
T5857-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Trametinib (DMSO solvate) |
Amphotericin B(100% DMSO) |
|||
E28XB0086-1 | EnoGene | 1ml | EUR 88.89 |
DMAO, 2mM in DMSO |
|||
40012-1 | Biotium | EA | EUR 292 |
OPTIONAL HEAD,3 INCH,FOR PROCESSING LARGER NUMBERS OF TUBES |
|||
480100 | CORNING | 1/pk | EUR 68.4 |
Description: Lab Equipment; Shakers & Mixers |
Paclitaxel (2mM in DMSO) |
|||
TXD01 | Cytoskeleton | 10 x 100 µl | EUR 220.48 |
MicroCrystal Mount Assortment, 2 each of numbers 1 - 12, on 18mm rods |
|||
M4-L18SP-A1 | MiTeGen | 20 MOUNTS | EUR 125 |
Description: MicroCrystal Mount Assortment, 2 each of numbers 1 - 12, on 18mm rods |
Amphotericin B(1% DMSO) |
|||
E28XB0086-10 | EnoGene | 10ml | EUR 101.59 |
Amphotericin B(1% DMSO) |
|||
E28XB0086-100 | EnoGene | 100ml | EUR 438.1 |
Embedding Molds - Silicone, Flat, Numbered Cavities - Opaque |
|||
23258-1 | Polysciences Europe GmbH | 1each | EUR 90 |
DMSO, Molecular Biology Grade |
|||
40470006-1 | Glycomatrix | 100 mL | EUR 88.18 |
DMSO, Molecular Biology Grade |
|||
40470006-2 | Glycomatrix | 250 mL | EUR 150.19 |
DMSO, Molecular Biology Grade |
|||
40470006-3 | Glycomatrix | 500 mL | EUR 279.26 |
MLN 8237 (Contain 10% DMSO) |
|||
M425115 | Toronto Research Chemicals | 10mg | EUR 287 |
Description: 1028486-01-2 |
EvaGreen®, 2000X in DMSO |
|||
31019-1 | Biotium | EA | EUR 219 |
Thiazole Red, 1mM in DMSO |
|||
40087-1 | Biotium | EA | EUR 305 |
Oxazole Gold, 10,000X in DMSO |
|||
40094-1 | Biotium | EA | EUR 205 |
DMSO, labeling grade, 1 mL |
|||
15050 | Lumiprobe | 1 mL | EUR 44.4 |
Bemetizide (1.0mg/ml in DMSO) |
|||
KIT9935 | Toronto Research Chemicals | 1x1ml | EUR 477 |
Description: 1824-52-8 |
Bictegravir (100 mg/mL in DMSO) |
|||
KIT8580 | Toronto Research Chemicals | 1x1ml | EUR 742 |
Description: 1611493-60-7 |
Cell Reservoir One(with DMSO) |
|||
07485-44 | NACALAI TESQUE | 100ML | EUR 73.5 |
Cell Reservoir One(with DMSO) |
|||
07485-86 | NACALAI TESQUE | 10ML | EUR 15.4 |
Phenobarbital (5.0mg/ml in DMSO) |
|||
KIT1825 | Toronto Research Chemicals | 5x1ml | EUR 800 |
Description: 50-06-6 |
Round Grid Mats, 12/pack White silicone rubber mats, with numbered compartments. |
|||
M-CEM-71172 | MiTeGen | - | EUR 83 |
Description: Round Grid Mats, 12/pack White silicone rubber mats, with numbered compartments. |
LAMP Greenâ„¢ *50X DMSO Solution* |
|||
17555 | AAT Bioquest | 100 ul | EUR 308 |
Description: Isothermal amplification methods provide detection of nucleic acid target sequence in a streamlined, exponential manner. |
LAMP Greenâ„¢ *50X DMSO Solution* |
|||
17555-100ul | AAT Bioquest | 100 ul | EUR 301 |
Description: Isothermal amplification methods provide detection of nucleic acid target sequence in a streamlined, exponential manner. |
DMSO Resistant Peel Seal Roll |
|||
PCR0854 | Scientific Laboratory Supplies | 1ROLL | EUR 1416.69 |
DMSO Resistant Peel Seal Roll |
|||
PCR0856 | Scientific Laboratory Supplies | 1ROLL | EUR 40.19 |
DMSO Resistant Peel Seal Roll |
|||
PCR0858 | Scientific Laboratory Supplies | 1ROLL | EUR 327.69 |
DMSO Resistant Peel Seal Roll |
|||
PCR0860 | Scientific Laboratory Supplies | 1ROLL | EUR 1449.36 |
DMSO Resistant Peel Seal Roll |
|||
PCR0862 | Scientific Laboratory Supplies | 1ROLL | EUR 1590.93 |
DMSO Resistant Peel Seal Roll |
|||
PCR0864 | Scientific Laboratory Supplies | 1ROLL | EUR 39.01 |
RedDot™2, 200X in DMSO |
|||
40061-1 | Biotium | 1mL | EUR 351 |
Description: N/A |
RedDot™2, 200X in DMSO |
|||
40061-1-1 | Biotium | EA | EUR 575 |
RedDot™2, 200X in DMSO |
|||
40061-T | Biotium | 25uL | EUR 91 |
Description: N/A |
RedDot™2, 200X in DMSO |
|||
40061-T-1 | Biotium | EA | EUR 91 |
Cell Reservoir One(without DMSO) |
|||
07579-24 | NACALAI TESQUE | 100ML | EUR 102.2 |
Cell Reservoir One(without DMSO) |
|||
07579-37 | NACALAI TESQUE | 10ML | EUR 18.9 |
Q4everâ„¢ Green *1250X DMSO Solution* |
|||
17608 | AAT Bioquest | 100 ul | EUR 155 |
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR). |
Q4everâ„¢ Green *1250X DMSO Solution* |
|||
17608-100ul | AAT Bioquest | 100 ul | EUR 151 |
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR). |
Q4everâ„¢ Green *1250X DMSO Solution* |
|||
17609 | AAT Bioquest | 2 ml | EUR 2070 |
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR). |
Q4everâ„¢ Green *1250X DMSO Solution* |
|||
17609-2ml | AAT Bioquest | 2 ml | EUR 2029 |
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR). |
Statebourne Biosystem 80 ICS - Vapour Phase 100 25 Cell Cryoboxes numbered racks 79 300 - EACH |
|||
CRY3316 | Scientific Laboratory Supplies | EACH | EUR 25825.91 |
Oxazole Red, 1 mM in DMSO |
|||
40105-1 | Biotium | EA | EUR 332 |
NucSpot® 470, 1000X in DMSO |
|||
40083-1 | Biotium | EA | EUR 364 |
NucSpot® 470, 1000X in DMSO |
|||
40083-T | Biotium | 20uL | EUR 63 |
Description: N/A |
NucSpot® 470, 1000X in DMSO |
|||
40083-T-1 | Biotium | EA | EUR 63 |
Oxazole Blue, 1 mM in DMSO |
|||
40091-1 | Biotium | EA | EUR 366 |
LysoView™ 650, 1000X IN DMSO |
|||
70059 | Biotium | 1UL | EUR 171 |
Description: N/A |
LysoView™ 650, 1000X IN DMSO |
|||
70059-1 | Biotium | EA | EUR 171 |
LysoView™ 540, 1000X in DMSO |
|||
70061 | Biotium | 50uL | EUR 173 |
Description: N/A |
LysoView™ 540, 1000X in DMSO |
|||
70061-1 | Biotium | EA | EUR 173 |
LysoView™ 405, 1000X in DMSO |
|||
70066 | Biotium | 50uL | EUR 169 |
Description: N/A |
LysoView™ 405, 1000X in DMSO |
|||
70066-1 | Biotium | EA | EUR 169 |
LysoView™ 488, 1000X in DMSO |
|||
70067 | Biotium | 50uL | EUR 169 |
Description: N/A |
LysoView™ 488, 1000X in DMSO |
|||
70067-1 | Biotium | EA | EUR 169 |
LysoView™ 550, 1000X in DMSO |
|||
70083 | Biotium | 1UL | EUR 162 |
Description: N/A |
LysoView™ 550, 1000X in DMSO |
|||
70083-1 | Biotium | EA | EUR 162 |
LysoView™ 594, 1000X in DMSO |
|||
70084 | Biotium | 1UL | EUR 162 |
Description: N/A |
LysoView™ 594, 1000X in DMSO |
|||
70084-1 | Biotium | EA | EUR 162 |
LysoView™ 640, 1000X in DMSO |
|||
70085 | Biotium | 1UL | EUR 162 |
Description: N/A |
LysoView™ 640, 1000X in DMSO |
|||
70085-1 | Biotium | EA | EUR 162 |
LysoView™ 680, 1000X in DMSO |
|||
70086 | Biotium | 1UL | EUR 210 |
Description: N/A |
LysoView™ 680, 1000X in DMSO |
|||
70086-1 | Biotium | EA | EUR 210 |
250mL DMSO Dimethyl Sulfoxide - EACH |
|||
25-950-CQC | Scientific Laboratory Supplies | EACH | EUR 128.25 |
EGTA AM *10 mM DMSO solution* |
|||
21006-1mL | AAT Bioquest | 1 mL | EUR 166 |
Description: EGTA AM is cell-permeable version of EGTA (ethylene glycol tetraacetic acid), a cell-permeable calcium chelator. |
TMRE, 2 mM solution in DMSO |
|||
70005 | Biotium | 0.5ML | EUR 140 |
Description: N/A |
TMRE, 2 mM solution in DMSO |
|||
70005-1 | Biotium | EA | EUR 140 |
ACETOSYRINGONE SOLUTION (100 mM) IN DMSO |
|||
A1104 | PhytoTechnology Laboratories | 10ML | EUR 65.63 |
Oxazole Yellow, 1 mM in DMSO |
|||
40089-1 | Biotium | EA | EUR 322 |
Cyanine7.5 azide, 100 uL, 10 mM/DMSO |
|||
16030 | Lumiprobe | 100 µl | EUR 129.6 |
Thiazole orange *10 mM in DMSO* |
|||
17519 | AAT Bioquest | 10 mL | EUR 88 |
Description: Thiazole orange is a fluorescent DNA-binding dye for reticulocyte analysis. |
Thiazole orange *10 mM in DMSO* |
|||
17519-10mL | AAT Bioquest | 10 mL | EUR 86 |
Description: Thiazole orange is a fluorescent DNA-binding dye for reticulocyte analysis. |
CYTO-13 *5 mM DMSO solution* |
|||
17553 | AAT Bioquest | 0.5 mL | EUR 227 |
Description: CYTO-13 is a fluorogenic, DNA-selective and cell-permeant dye for analyzing DNA content in living cells. |
CYTO-13 *5 mM DMSO solution* |
|||
17553-05mL | AAT Bioquest | 0.5 mL | EUR 222 |
Description: CYTO-13 is a fluorogenic, DNA-selective and cell-permeant dye for analyzing DNA content in living cells. |
Thiazole Orange, 10 mM in DMSO |
|||
40077-1 | Biotium | EA | EUR 107 |
Thiazole Green, 10, 000X in DMSO |
|||
40086-0.5mL | Biotium | 0.5mL | EUR 155 |
Description: N/A |
Thiazole Green, 10, 000X in DMSO |
|||
40086-0.5mL-1 | Biotium | EA | EUR 155 |
Thiazole Green, 10, 000X in DMSO |
|||
40086-1mL | Biotium | 1mL | EUR 266 |
Description: N/A |
Thiazole Green, 10, 000X in DMSO |
|||
40086-1mL-1 | Biotium | EA | EUR 266 |
DiagNano™ ZnO Quantum Dots, DMSO, 530 nm |
|||
DNG-NX02 | Creative Diagnostics | 5 ml | EUR 1512 |
Nor Oxymorphone (1.0mg/ml in DMSO) |
|||
KIT0025 | Toronto Research Chemicals | 1x1ml | EUR 800 |
Description: 33522-95-1 |
Phosphatase Inhibitor Cocktail II (100× DMSO) |
|||
C0003-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Phosphatase Inhibitor Cocktail II (100× DMSO) |
Phosphatase Inhibitor Cocktail II (100× DMSO) |
|||
C0003-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Phosphatase Inhibitor Cocktail II (100× DMSO) |