TP0136 anti-syphilis antibodies in development are poorly understood. This study aimed to determine the effect of anti-TP0136 antibodies on lesion development in infected rabbit models. rTP0136 intramuscular injection into rabbits in the immunized group (n = 4) induce high titers of anti TP0136-antibody, and rabbit then challenged with 105T. pallidum per site along their back. lesion development was observed, and the injection sites were biopsied for tp0574 mRNA and histological analysis every week until the wound is healed. Rabbits in the control group were injected with normal saline instead rTP0136. Decent T. pallidum in rabbits challenged assessed by a test rabbit infectivity.
Lesions in the immunized group took longer to heal than in the control group (42 d vs 28 d, P <0.001) and had a real level higher than the number of cellular infiltrates. MRNA levels of tp0574 the immunized group was significantly higher than in the control group (P <0.05). Decent T. pallidum detected in the lymph nodes of rabbits in both groups were immunized and control. Our study shows that a high titer antibody anti TP0136-promoted infiltration of inflammatory cells into the local lesions and tissue damage intensive, thereby delaying wound healing, and does not have a protective effect on the occurrence of syphilis in a rabbit model.
 DMSO, anhydrous |
|
90082 |
Biotium |
10ML |
EUR 87.6 |
|
Description: Minimum order quantity: 1 unit of 10ML |
 Human Mitochondrial DNA Copy Number Kit |
|
MCN1 |
Detroit R&D |
1 Kit |
EUR 418.8 |
 Rat Mitochondrial DNA Copy Number Kit |
|
MCN2 |
Detroit R&D |
1 Kit |
EUR 418.8 |
 Mouse Mitochondrial DNA Copy Number Kit |
|
MCN3 |
Detroit R&D |
1 Kit |
EUR 418.8 |
 CAS antibody |
|
70R-31499 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal CAS antibody |
 Trametinib DMSO solvate |
|
A3887-10 |
ApexBio |
10 mg |
EUR 129.6 |
|
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase. |
Trametinib DMSO solvate |
|
A3887-100 |
ApexBio |
100 mg |
EUR 224.4 |
|
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase. |
Trametinib DMSO solvate |
|
A3887-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 135.6 |
|
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase. |
Trametinib DMSO solvate |
|
A3887-50 |
ApexBio |
50 mg |
EUR 170.4 |
|
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase. |
) Dimethyl sulfoxide (DMSO) |
|
D0231 |
Bio Basic |
500ml |
EUR 88.55 |
|
|
 piggyBac qPCR copy number kit, 20 reactions |
|
PBC100A-1 |
SBI |
20 reactions |
EUR 397.2 |
|
|
 DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7* |
|
17575 |
AAT Bioquest |
0.2 ml |
EUR 262.8 |
|
|
 DMAO, 2mM in DMSO |
|
40012 |
Biotium |
1ML |
EUR 355.2 |
|
Description: Minimum order quantity: 1 unit of 1ML |
 EvaGreen, 2000X in DMSO |
|
31019 |
Biotium |
50uL |
EUR 294 |
|
Description: Minimum order quantity: 1 unit of 50uL |
 CAS Polyclonal Antibody |
|
ABP50845-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
|
|
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80 |
CAS Polyclonal Antibody |
|
ABP50845-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
|
|
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80 |
CAS Polyclonal Antibody |
|
ABP50845-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
|
|
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80 |
 CAS Blocking Peptide |
|
AF9032-BP |
Affbiotech |
1mg |
EUR 234 |
CAS Polyclonal Antibody |
|
ES1844-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against CAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IP, IF, WB, ELISA |
CAS Polyclonal Antibody |
|
ES1844-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against CAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IP, IF, WB, ELISA |
 p130 Cas antibody |
|
70R-31036 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal p130 Cas antibody |
) CAS antibody (Tyr165) |
|
70R-31498 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal CAS antibody (Tyr165) |
) CAS antibody (Tyr249) |
|
70R-31500 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal CAS antibody (Tyr249) |
CAS Polyclonal Antibody |
|
40671-100ul |
SAB |
100ul |
EUR 302.4 |
CAS Polyclonal Antibody |
|
40671-50ul |
SAB |
50ul |
EUR 224.4 |
 p130 Cas Antibody |
|
20-abx012761 |
Abbexa |
-
EUR 376.80
-
EUR 117.60
-
EUR 477.60
-
EUR 594.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
|
 Anti-CAS Antibody |
|
A04496 |
BosterBio |
100ul |
EUR 476.4 |
|
Description: Rabbit Polyclonal Antibody for CAS Antibody (CSE1L) detection.tested for IP, WB in Human. |
 Anti-CAS antibody |
|
STJ92006 |
St John's Laboratory |
200 µl |
EUR 236.4 |
|
Description: Rabbit polyclonal to CAS. |
 DiYO™-3 [equivalent to YO-YO®-3] *5 mM DMSO Solution* *CAS 156312-20-8* |
|
17581 |
AAT Bioquest |
0.2 ml |
EUR 262.8 |
|
|
 TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2* |
|
17571 |
AAT Bioquest |
0.2 ml |
EUR 262.8 |
|
|
 TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8* |
|
17572 |
AAT Bioquest |
0.2 ml |
EUR 262.8 |
|
|
 LysoView 540, 1000X in DMSO |
|
70061 |
Biotium |
50uL |
EUR 246 |
|
Description: Minimum order quantity: 1 unit of 50uL |
LysoView 540, 1000X in DMSO |
|
70061-T |
Biotium |
10uL |
EUR 112.8 |
|
Description: Minimum order quantity: 1 unit of 10uL |
 LysoViewâ„¢ 405, 1000X in DMSO |
|
70066 |
Biotium |
50uL |
EUR 241.2 |
|
Description: Minimum order quantity: 1 unit of 50uL |
 LysoViewâ„¢ 488, 1000X in DMSO |
|
70067 |
Biotium |
50uL |
EUR 241.2 |
|
Description: Minimum order quantity: 1 unit of 50uL |
 MitoViewâ„¢ 720, 1000X in DMSO |
|
70068 |
Biotium |
20X50UG |
EUR 306 |
|
Description: Minimum order quantity: 1 unit of 20X50UG |
 RedDot 2, 200X in DMSO |
|
40061 |
Biotium |
250uL |
EUR 434.4 |
|
Description: Minimum order quantity: 1 unit of 250uL |
RedDot 2, 200X in DMSO |
|
40061-1 |
Biotium |
1mL |
EUR 673.2 |
|
Description: Minimum order quantity: 1 unit of 1mL |
RedDot 2, 200X in DMSO |
|
40061-T |
Biotium |
25uL |
EUR 157.2 |
|
Description: Minimum order quantity: 1 unit of 25uL |
 Thiazole Orange, 10mM in DMSO |
|
40077 |
Biotium |
1mL |
EUR 174 |
|
Description: Minimum order quantity: 1 unit of 1mL |
 NucSpot 470, 1000X in DMSO |
|
40083 |
Biotium |
200uL |
EUR 446.4 |
|
Description: Minimum order quantity: 1 unit of 200uL |
NucSpot 470, 1000X in DMSO |
|
40083-T |
Biotium |
20uL |
EUR 127.2 |
|
Description: Minimum order quantity: 1 unit of 20uL |
 Thiazole Red, 1mM in DMSO |
|
40087 |
Biotium |
1mL |
EUR 384 |
|
Description: Minimum order quantity: 1 unit of 1mL |
 Oxazole Yellow, 1mM in DMSO |
|
40089 |
Biotium |
1mL |
EUR 403.2 |
|
Description: Minimum order quantity: 1 unit of 1mL |
 DMSO, labeling grade, 1 mL |
|
15050 |
Lumiprobe |
1 mL |
EUR 44.4 |
 p130 Cas Blocking Peptide |
|
AF7826-BP |
Affbiotech |
1mg |
EUR 234 |
p130 Cas Blocking Peptide |
|
AF7827-BP |
Affbiotech |
1mg |
EUR 234 |
p130 Cas Blocking Peptide |
|
AF4748-BP |
Affbiotech |
1mg |
EUR 234 |
p130 Cas Blocking Peptide |
|
AF6350-BP |
Affbiotech |
1mg |
EUR 234 |
 CAS Polyclonal Conjugated Antibody |
|
C40671 |
SAB |
100ul |
EUR 476.4 |
 p130 Cas Polyclonal Antibody |
|
ES3093-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p130 Cas Polyclonal Antibody |
|
ES3093-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p130 Cas Polyclonal Antibody |
|
ES3094-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p130 Cas Polyclonal Antibody |
|
ES3094-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
) p130 Cas antibody (Tyr410) |
|
70R-31035 |
Fitzgerald |
100 ug |
EUR 392.4 |
|
Description: Rabbit polyclonal p130 Cas antibody (Tyr410) |
 AE-1477 EzBlock CAS |
|
2332617 |
Atto |
3unit |
EUR 352.8 |
|
Description: Casei n for wer st er n bl ot t i ng |
 Antibody) p130 Cas (pY410) Antibody |
|
abx010316-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
|
 Antibody) p130 Cas (pT249) Antibody |
|
20-abx009713 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
|
p130 Cas Polyclonal Antibody |
|
ABP52094-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165 |
p130 Cas Polyclonal Antibody |
|
ABP52094-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165 |
p130 Cas Polyclonal Antibody |
|
ABP52094-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165 |
p130 Cas Polyclonal Antibody |
|
ABP52095-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410 |
p130 Cas Polyclonal Antibody |
|
ABP52095-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410 |
p130 Cas Polyclonal Antibody |
|
ABP52095-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
|
|
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410 |
 Anti-p130 Cas antibody |
|
STJ94853 |
St John's Laboratory |
200 µl |
EUR 236.4 |
|
Description: Rabbit polyclonal to p130 Cas. |
Anti-p130 Cas antibody |
|
STJ94854 |
St John's Laboratory |
200 µl |
EUR 236.4 |
|
Description: Rabbit polyclonal to p130 Cas. |
) Donkey Anti-Sheep IgG, Salt Fractionation (Bulk) |
|
30326-CAS-BLK |
Alpha Diagnostics |
1g; bulk |
Ask for price |
) Cycloheximide Solution (10% in DMSO Sterile) |
|
C084-10x1ML |
TOKU-E |
10x1 mL |
EUR 232.8 |
Cycloheximide Solution (10% in DMSO Sterile) |
|
C084-1ML |
TOKU-E |
1 mL |
EUR 64.8 |
 TMRE, 2 mM solution in DMSO |
|
70005 |
Biotium |
0.5ML |
EUR 178.8 |
|
Description: Minimum order quantity: 1 unit of 0.5ML |
 6-TAMRA, SE in DMSO:100uL |
|
90097 |
Biotium |
100uL |
EUR 368.4 |
|
Description: Minimum order quantity: 1 unit of 100uL |
) 6-Rox, SE in DMSO:(100uL) |
|
90098 |
Biotium |
100uL |
EUR 368.4 |
|
Description: Minimum order quantity: 1 unit of 100uL |
 EGTA AM *10 mM DMSO solution* |
|
21006 |
AAT Bioquest |
1 mL |
EUR 211.2 |
|
|
 Ethidium homodimer I, 2mM DMSO solution |
|
40014 |
Biotium |
0.5ML |
EUR 308.4 |
|
Description: Minimum order quantity: 1 unit of 0.5ML |
 Ethidium homodimer III, 1mM in DMSO |
|
40051 |
Biotium |
200uL |
EUR 374.4 |
|
Description: Minimum order quantity: 1 unit of 200uL |
 Thiazole Red Homodimer, 1mM in DMSO |
|
40080 |
Biotium |
200uL |
EUR 426 |
|
Description: Minimum order quantity: 1 unit of 200uL |
 NucSpot Live 488, 1000X in DMSO |
|
40081 |
Biotium |
50uL |
EUR 426 |
|
Description: Minimum order quantity: 1 unit of 50uL |
NucSpot Live 488, 1000X in DMSO |
|
40081-T |
Biotium |
10uL |
EUR 139.2 |
|
Description: Minimum order quantity: 1 unit of 10uL |
 NucSpot Far-Red, 1000X in DMSO |
|
40085 |
Biotium |
0.5mL |
EUR 675.6 |
|
Description: Minimum order quantity: 1 unit of 0.5mL |
NucSpot Far-Red, 1000X in DMSO |
|
40085-T |
Biotium |
50uL |
EUR 157.2 |
|
Description: Minimum order quantity: 1 unit of 50uL |
 Thiazole Green, 10, 000X in DMSO |
|
40086-0.5mL |
Biotium |
0.5mL |
EUR 225.6 |
|
Description: Minimum order quantity: 1 unit of 0.5mL |
Thiazole Green, 10, 000X in DMSO |
|
40086-1mL |
Biotium |
1mL |
EUR 344.4 |
|
Description: Minimum order quantity: 1 unit of 1mL |
 Thiazole orange *10 mM in DMSO* |
|
17519 |
AAT Bioquest |
10 mL |
EUR 138 |
|
|
 Calcein AM, 4mm in anhydrous DMSO |
|
80011-1 |
Biotium |
100uL |
EUR 271.2 |
|
Description: Minimum order quantity: 1 unit of 100uL |
 CYTO-13 *5 mM DMSO solution* |
|
17553 |
AAT Bioquest |
0.5 mL |
EUR 222 |
 LAMP Green® *50X DMSO Solution* |
|
17555 |
AAT Bioquest |
100 ul |
EUR 301 |
 Q4ever™ Green *1250X DMSO Solution* |
|
17608 |
AAT Bioquest |
100 ul |
EUR 151 |
Q4ever™ Green *1250X DMSO Solution* |
|
17609 |
AAT Bioquest |
2 ml |
EUR 2029 |
 Antibody) Phospho-p130 Cas (Tyr410) Antibody |
|
AF3350 |
Affbiotech |
200ul |
EUR 420 |
 Antibody) Phospho-p130 Cas (Tyr165) Antibody |
|
AF4448 |
Affbiotech |
200ul |
EUR 540 |
 Antibody) Phospho-p130 Cas (Tyr267) Antibody |
|
AF7326 |
Affbiotech |
200ul |
EUR 540 |
 Antibody) Phospho-p130 Cas (Tyr387) Antibody |
|
AF7327 |
Affbiotech |
200ul |
EUR 540 |
 Antibody) Phospho-p130 Cas (Tyr249) Antibody |
|
AF2375 |
Affbiotech |
200ul |
EUR 420 |
 Coelenterazine *CAS#: 55779-48-1* |
|
21150 |
AAT Bioquest |
250 ug |
EUR 138 |
|
|
Coelenterazine *CAS#: 55779-48-1* |
|
21156 |
AAT Bioquest |
1 mg |
EUR 158.4 |
|
|
Coelenterazine *CAS#: 55779-48-1* |
|
21166 |
AAT Bioquest |
10 mg |
EUR 576 |
|
|
 Zinquin *CAS#: 151606-29-0* |
|
21260 |
AAT Bioquest |
5 mg |
EUR 158.4 |
|
|
