Effect of anti-TP0136 antibodies on the progression of lesions in an infected rabbit model.

TP0136 anti-syphilis antibodies in development are poorly understood. This study aimed to determine the effect of anti-TP0136 antibodies on lesion development in infected rabbit models. rTP0136 intramuscular injection into rabbits in the immunized group (n = 4) induce high titers of anti TP0136-antibody, and rabbit then challenged with 105T. pallidum per site along their back. lesion development was observed, and the injection sites were biopsied for tp0574 mRNA and histological analysis every week until the wound is healed. Rabbits in the control group were injected with normal saline instead rTP0136. Decent T. pallidum in rabbits challenged assessed by a test rabbit infectivity.

Lesions in the immunized group took longer to heal than in the control group (42 d vs 28 d, P <0.001) and had a real level higher than the number of cellular infiltrates. MRNA levels of tp0574 the immunized group was significantly higher than in the control group (P <0.05). Decent T. pallidum detected in the lymph nodes of rabbits in both groups were immunized and control. Our study shows that a high titer antibody anti TP0136-promoted infiltration of inflammatory cells into the local lesions and tissue damage intensive, thereby delaying wound healing, and does not have a protective effect on the occurrence of syphilis in a rabbit model.

Kinesis See Part Number P-332 - PK10

CHR4033 PK10
EUR 22.38

piggyBac qPCR copy number kit, 20 reactions  

PBC100A-1 20 reactions
EUR 275

copy number positive control for custom assay

Z-any-std each
EUR 198

Drain Tap Assembly to suit baths with serial number: 75100 - EACH

BAT7360 EACH
EUR 89.1

copy number positive control for custom rat assay

Z-ra-std each
EUR 198
Description: Control

copy number positive control for custom mouse assay

Z-mo-std each
EUR 198

copy number positive control for custom human assay

Z-hu-std each
EUR 217
Description: Control

Kinesis Septa TCS 11mm Bought as part number without /S - EACH

CHR1750 EACH
EUR 4.8

Kinesis Obsolete see part number M-653 Headless; 10-32; 1/16

CHR3683 PK10
EUR 50.16

Trametinib, DMSO Solvate [CAS# 1187431-43-1]

T-8188 10 mg
EUR 38

DMSO

40470004-1 500 mL
EUR 69.23

DMSO

40470004-2 1 L
EUR 107.61

DMSO

40470004-3 100 mL
EUR 34.04

DMSO

40470004-4 250 mL
EUR 41.19

DMSO

40470004-5 50 mL
EUR 22.74

DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7*

17575 0.2 ml
EUR 227
Description: DiTO™-1 is chemically equivalent to TOTO®-1 (TOTO® is the trademark of Invitrogen).

DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7*

17575-02ml 0.2 ml
EUR 222
Description: DiTO™-1 is chemically equivalent to TOTO®-1 (TOTO® is the trademark of Invitrogen).

DiYO™-3 [equivalent to YOYO®-3] *5 mM DMSO Solution* *CAS 156312-20-8*

17581 0.2 ml
EUR 227
Description: DiYO™-3 is chemically equivalent to YOYO®-3 (YOYO® is the trademark of Invitrogen).

DiYO™-3 [equivalent to YOYO®-3] *5 mM DMSO Solution* *CAS 156312-20-8*

17581-02ml 0.2 ml
EUR 222
Description: DiYO™-3 is chemically equivalent to YOYO®-3 (YOYO® is the trademark of Invitrogen).

DMSO, anhydrous

90082-1 EA
EUR 31

Dimethylsulfoxide (DMSO), 500ml

PC0906-500ml each Ask for price

Dry DMSO, 2ML

X022-2ML 2ML
EUR 37

Dry DMSO, 4ML

X022-4ML 4ML
EUR 54

Dry DMSO, 5ML

X022-5ML 5ML
EUR 59

Dry DMSO, 14ML

X022-14ML 14ML
EUR 109

Dry DMSO, 20ML

X022-20ML 20ML
EUR 168

MAGNETIC NUMBERS WHITE 18/23MM AB Labels

224065 Vel of 257 Label(s)
EUR 41.64
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille

MAGNETIC NUMBERS WHITE 39/43MM AB Labels

224066 Vel of 85 Label(s)
EUR 45.2
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille

MAGNETIC NUMBERS YELLOW 18/23MM AB Labels

224063 Vel of 257 Label(s)
EUR 41.64
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille

MAGNETIC NUMBERS YELLOW 39/43MM AB Labels

224064 Vel of 85 Label(s)
EUR 45.2
Description: Description Dutch: Magnetische cijferset; Description French: Chiffres magnétiques par feuille

TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2*

17571 0.2 ml
EUR 227
Description: TWO-PRO™-1 is chemically equivalent to TO-PRO®-1 (TO-PRO® is the trademark of Invitrogen).

TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2*

17571-02ml 0.2 ml
EUR 222
Description: TWO-PRO™-1 is chemically equivalent to TO-PRO®-1 (TO-PRO® is the trademark of Invitrogen).

TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8*

17572 0.2 ml
EUR 227
Description: TWO-PRO™-3 is chemically equivalent to TO-PRO®-3 (TO-PRO® is the trademark of Invitrogen).

TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8*

17572-02ml 0.2 ml
EUR 222
Description: TWO-PRO™-3 is chemically equivalent to TO-PRO®-3 (TO-PRO® is the trademark of Invitrogen).

Trametinib DMSO solvate

123211 10.0mg
EUR 90

Dimethyl sulfoxide (DMSO)

D0231 500ml
EUR 88.55

Trametinib DMSO solvate

A3887-10 10 mg
EUR 40
Description: Allosteric MEK1/MEK2 kinase inhibitor

Trametinib DMSO solvate

A3887-100 100 mg
EUR 95
Description: Allosteric MEK1/MEK2 kinase inhibitor

Trametinib DMSO solvate

A3887-5.1 10 mM (in 1mL DMSO)
EUR 44
Description: Allosteric MEK1/MEK2 kinase inhibitor

Trametinib DMSO solvate

A3887-50 50 mg
EUR 64
Description: Allosteric MEK1/MEK2 kinase inhibitor

Trametinib (DMSO solvate)

HY-10999A 100mg
EUR 256.8

Trametinib (DMSO Solvate)

T314310 100mg
EUR 800
Description: 1187431-43-1

Trametinib (DMSO solvate)

T5857-10mg 10mg Ask for price
Description: Trametinib (DMSO solvate)

Trametinib (DMSO solvate)

T5857-1g 1g Ask for price
Description: Trametinib (DMSO solvate)

Trametinib (DMSO solvate)

T5857-1mg 1mg Ask for price
Description: Trametinib (DMSO solvate)

Trametinib (DMSO solvate)

T5857-50mg 50mg Ask for price
Description: Trametinib (DMSO solvate)

Trametinib (DMSO solvate)

T5857-5mg 5mg Ask for price
Description: Trametinib (DMSO solvate)

Amphotericin B(100% DMSO)

E28XB0086-1 1ml
EUR 88.89

DMAO, 2mM in DMSO

40012-1 EA
EUR 292

OPTIONAL HEAD,3 INCH,FOR PROCESSING LARGER NUMBERS OF TUBES

480100 1/pk
EUR 68.4
Description: Lab Equipment; Shakers & Mixers

Paclitaxel (2mM in DMSO)

TXD01 10 x 100 µl
EUR 220.48

MicroCrystal Mount Assortment, 2 each of numbers 1 - 12, on 18mm rods

M4-L18SP-A1 20 MOUNTS
EUR 125
Description: MicroCrystal Mount Assortment, 2 each of numbers 1 - 12, on 18mm rods

Amphotericin B(1% DMSO)

E28XB0086-10 10ml
EUR 101.59

Amphotericin B(1% DMSO)

E28XB0086-100 100ml
EUR 438.1

Embedding Molds - Silicone, Flat, Numbered Cavities - Opaque

23258-1 1each
EUR 90

DMSO, Molecular Biology Grade

40470006-1 100 mL
EUR 88.18

DMSO, Molecular Biology Grade

40470006-2 250 mL
EUR 150.19

DMSO, Molecular Biology Grade

40470006-3 500 mL
EUR 279.26

MLN 8237 (Contain 10% DMSO)

M425115 10mg
EUR 287
Description: 1028486-01-2

EvaGreen®, 2000X in DMSO

31019-1 EA
EUR 219

Thiazole Red, 1mM in DMSO

40087-1 EA
EUR 305

Oxazole Gold, 10,000X in DMSO

40094-1 EA
EUR 205

DMSO, labeling grade, 1 mL

15050 1 mL
EUR 44.4

Bemetizide (1.0mg/ml in DMSO)

KIT9935 1x1ml
EUR 477
Description: 1824-52-8

Bictegravir (100 mg/mL in DMSO)

KIT8580 1x1ml
EUR 742
Description: 1611493-60-7

Cell Reservoir One(with DMSO)

07485-44 100ML
EUR 73.5

Cell Reservoir One(with DMSO)

07485-86 10ML
EUR 15.4

Phenobarbital (5.0mg/ml in DMSO)

KIT1825 5x1ml
EUR 800
Description: 50-06-6

Round Grid Mats, 12/pack White silicone rubber mats, with numbered compartments.

M-CEM-71172 -
EUR 83
Description: Round Grid Mats, 12/pack White silicone rubber mats, with numbered compartments.

LAMP Greenâ„¢ *50X DMSO Solution*

17555 100 ul
EUR 308
Description: Isothermal amplification methods provide detection of nucleic acid target sequence in a streamlined, exponential manner.

LAMP Greenâ„¢ *50X DMSO Solution*

17555-100ul 100 ul
EUR 301
Description: Isothermal amplification methods provide detection of nucleic acid target sequence in a streamlined, exponential manner.

DMSO Resistant Peel Seal Roll

PCR0854 1ROLL
EUR 1416.69

DMSO Resistant Peel Seal Roll

PCR0856 1ROLL
EUR 40.19

DMSO Resistant Peel Seal Roll

PCR0858 1ROLL
EUR 327.69

DMSO Resistant Peel Seal Roll

PCR0860 1ROLL
EUR 1449.36

DMSO Resistant Peel Seal Roll

PCR0862 1ROLL
EUR 1590.93

DMSO Resistant Peel Seal Roll

PCR0864 1ROLL
EUR 39.01

RedDot™2, 200X in DMSO

40061-1 1mL
EUR 351
Description: N/A

RedDot™2, 200X in DMSO

40061-1-1 EA
EUR 575

RedDot™2, 200X in DMSO

40061-T 25uL
EUR 91
Description: N/A

RedDot™2, 200X in DMSO

40061-T-1 EA
EUR 91

Cell Reservoir One(without DMSO)

07579-24 100ML
EUR 102.2

Cell Reservoir One(without DMSO)

07579-37 10ML
EUR 18.9

Q4everâ„¢ Green *1250X DMSO Solution*

17608 100 ul
EUR 155
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR).

Q4everâ„¢ Green *1250X DMSO Solution*

17608-100ul 100 ul
EUR 151
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR).

Q4everâ„¢ Green *1250X DMSO Solution*

17609 2 ml
EUR 2070
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR).

Q4everâ„¢ Green *1250X DMSO Solution*

17609-2ml 2 ml
EUR 2029
Description: A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR).

Statebourne Biosystem 80 ICS - Vapour Phase 100 25 Cell Cryoboxes numbered racks 79 300 - EACH

CRY3316 EACH
EUR 25825.91

Oxazole Red, 1 mM in DMSO

40105-1 EA
EUR 332

NucSpot® 470, 1000X in DMSO

40083-1 EA
EUR 364

NucSpot® 470, 1000X in DMSO

40083-T 20uL
EUR 63
Description: N/A

NucSpot® 470, 1000X in DMSO

40083-T-1 EA
EUR 63

Oxazole Blue, 1 mM in DMSO

40091-1 EA
EUR 366

LysoView™ 650, 1000X IN DMSO

70059 1UL
EUR 171
Description: N/A

LysoView™ 650, 1000X IN DMSO

70059-1 EA
EUR 171

LysoView™ 540, 1000X in DMSO

70061 50uL
EUR 173
Description: N/A

LysoView™ 540, 1000X in DMSO

70061-1 EA
EUR 173

LysoView™ 405, 1000X in DMSO

70066 50uL
EUR 169
Description: N/A

LysoView™ 405, 1000X in DMSO

70066-1 EA
EUR 169

LysoView™ 488, 1000X in DMSO

70067 50uL
EUR 169
Description: N/A

LysoView™ 488, 1000X in DMSO

70067-1 EA
EUR 169

LysoView™ 550, 1000X in DMSO

70083 1UL
EUR 162
Description: N/A

LysoView™ 550, 1000X in DMSO

70083-1 EA
EUR 162

LysoView™ 594, 1000X in DMSO

70084 1UL
EUR 162
Description: N/A

LysoView™ 594, 1000X in DMSO

70084-1 EA
EUR 162

LysoView™ 640, 1000X in DMSO

70085 1UL
EUR 162
Description: N/A

LysoView™ 640, 1000X in DMSO

70085-1 EA
EUR 162

LysoView™ 680, 1000X in DMSO

70086 1UL
EUR 210
Description: N/A

LysoView™ 680, 1000X in DMSO

70086-1 EA
EUR 210

250mL DMSO Dimethyl Sulfoxide - EACH

25-950-CQC EACH
EUR 128.25

EGTA AM *10 mM DMSO solution*

21006-1mL 1 mL
EUR 166
Description: EGTA AM is cell-permeable version of EGTA (ethylene glycol tetraacetic acid), a cell-permeable calcium chelator.

TMRE, 2 mM solution in DMSO

70005 0.5ML
EUR 140
Description: N/A

TMRE, 2 mM solution in DMSO

70005-1 EA
EUR 140

ACETOSYRINGONE SOLUTION (100 mM) IN DMSO

A1104 10ML
EUR 65.63

Oxazole Yellow, 1 mM in DMSO

40089-1 EA
EUR 322

Cyanine7.5 azide, 100 uL, 10 mM/DMSO

16030 100 µl
EUR 129.6

Thiazole orange *10 mM in DMSO*

17519 10 mL
EUR 88
Description: Thiazole orange is a fluorescent DNA-binding dye for reticulocyte analysis.

Thiazole orange *10 mM in DMSO*

17519-10mL 10 mL
EUR 86
Description: Thiazole orange is a fluorescent DNA-binding dye for reticulocyte analysis.

CYTO-13 *5 mM DMSO solution*

17553 0.5 mL
EUR 227
Description: CYTO-13 is a fluorogenic, DNA-selective and cell-permeant dye for analyzing DNA content in living cells.

CYTO-13 *5 mM DMSO solution*

17553-05mL 0.5 mL
EUR 222
Description: CYTO-13 is a fluorogenic, DNA-selective and cell-permeant dye for analyzing DNA content in living cells.

Thiazole Orange, 10 mM in DMSO

40077-1 EA
EUR 107

Thiazole Green, 10, 000X in DMSO

40086-0.5mL 0.5mL
EUR 155
Description: N/A

Thiazole Green, 10, 000X in DMSO

40086-0.5mL-1 EA
EUR 155

Thiazole Green, 10, 000X in DMSO

40086-1mL 1mL
EUR 266
Description: N/A

Thiazole Green, 10, 000X in DMSO

40086-1mL-1 EA
EUR 266

DiagNano™ ZnO Quantum Dots, DMSO, 530 nm

DNG-NX02 5 ml
EUR 1512

Nor Oxymorphone (1.0mg/ml in DMSO)

KIT0025 1x1ml
EUR 800
Description: 33522-95-1

Phosphatase Inhibitor Cocktail II (100× DMSO)

C0003-10mg 10mg Ask for price
Description: Phosphatase Inhibitor Cocktail II (100× DMSO)

Phosphatase Inhibitor Cocktail II (100× DMSO)

C0003-1g 1g Ask for price
Description: Phosphatase Inhibitor Cocktail II (100× DMSO)
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