Effect of anti-TP0136 antibodies on the progression of lesions in an infected rabbit model.

TP0136 anti-syphilis antibodies in development are poorly understood. This study aimed to determine the effect of anti-TP0136 antibodies on lesion development in infected rabbit models. rTP0136 intramuscular injection into rabbits in the immunized group (n = 4) induce high titers of anti TP0136-antibody, and rabbit then challenged with 105T. pallidum per site along their back. lesion development was observed, and the injection sites were biopsied for tp0574 mRNA and histological analysis every week until the wound is healed. Rabbits in the control group were injected with normal saline instead rTP0136. Decent T. pallidum in rabbits challenged assessed by a test rabbit infectivity.

Lesions in the immunized group took longer to heal than in the control group (42 d vs 28 d, P <0.001) and had a real level higher than the number of cellular infiltrates. MRNA levels of tp0574 the immunized group was significantly higher than in the control group (P <0.05). Decent T. pallidum detected in the lymph nodes of rabbits in both groups were immunized and control. Our study shows that a high titer antibody anti TP0136-promoted infiltration of inflammatory cells into the local lesions and tissue damage intensive, thereby delaying wound healing, and does not have a protective effect on the occurrence of syphilis in a rabbit model.

3100 ug/mL Ethylene Glycol in DMSO

USP-S1952-DMSO 1ML
EUR 98.04

50000 ug/mL 111-Trichloroethane in DMSO

USP-S3605-DMSO 1ML
EUR 98.04

1900 ug/mL 1 4-Dioxane in DMSO

USP-S1715-DMSO 1ML
EUR 98.04

DMSO, anhydrous

90082 10ML
EUR 87.6
Description: Minimum order quantity: 1 unit of 10ML

Human Mitochondrial DNA Copy Number Kit

MCN1 1 Kit
EUR 418.8

Rat Mitochondrial DNA Copy Number Kit

MCN2 1 Kit
EUR 418.8

Mouse Mitochondrial DNA Copy Number Kit

MCN3 1 Kit
EUR 418.8

Kinesis See Part Number P-332

CHR4033 PK10
EUR 15.96

ELISA Kit Target

Catalog-Number Kit Size
EUR 60

CAS Antibody

AF9032 200ul
EUR 420

CAS antibody

70R-31499 100 ug
EUR 392.4
Description: Rabbit polyclonal CAS antibody

CAS Antibody

ABF9032 100 ug
EUR 525.6

Trametinib DMSO solvate

A3887-10 10 mg
EUR 129.6
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase.

Trametinib DMSO solvate

A3887-100 100 mg
EUR 224.4
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase.

Trametinib DMSO solvate

A3887-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase.

Trametinib DMSO solvate

A3887-50 50 mg
EUR 170.4
Description: Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase.

Dimethyl sulfoxide (DMSO)

D0231 500ml
EUR 88.55

Trametinib (DMSO solvate)

HY-10999A 100mg
EUR 256.8

Dry DMSO, 14ML

X022-14ML 14ML
EUR 171.6

Dry DMSO, 20ML

X022-20ML 20ML
EUR 232.8

Dry DMSO, 2ML

X022-2ML 2ML
EUR 112.8

Dry DMSO, 4ML

X022-4ML 4ML
EUR 139.2

Dry DMSO, 5ML

X022-5ML 5ML
EUR 146.4

piggyBac qPCR copy number kit, 20 reactions  

PBC100A-1 20 reactions
EUR 397.2

DiTO™-1 [equivalent to TOTO®-1] *5 mM DMSO Solution* *CAS 143413-84-7*

17575 0.2 ml
EUR 262.8

DMAO, 2mM in DMSO

40012 1ML
EUR 355.2
Description: Minimum order quantity: 1 unit of 1ML

EvaGreen, 2000X in DMSO

31019 50uL
EUR 294
Description: Minimum order quantity: 1 unit of 50uL

250mL DMSO Dimethyl Sulfoxide

25-950-CQC EACH
EUR 102.6

CAS Polyclonal Antibody

ABP50845-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80

CAS Polyclonal Antibody

ABP50845-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80

CAS Polyclonal Antibody

ABP50845-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of CAS from Human. This CAS antibody is for WB, IHC-P, IP, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human CAS at AA range: 1-80

p130 Cas Antibody

AF7826 200ul
EUR 540

p130 Cas Antibody

AF7827 200ul
EUR 540

CAS Blocking Peptide

AF9032-BP 1mg
EUR 234

p130 Cas Antibody

AF4748 200ul
EUR 540

p130 Cas Antibody

AF6350 200ul
EUR 420

p130 Cas Antibody

AF2675 100ul
EUR 420

CAS Polyclonal Antibody

ES1844-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against CAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IP, IF, WB, ELISA

CAS Polyclonal Antibody

ES1844-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against CAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IP, IF, WB, ELISA

p130 Cas antibody

70R-31036 100 ug
EUR 392.4
Description: Rabbit polyclonal p130 Cas antibody

CAS antibody (Tyr165)

70R-31498 100 ug
EUR 392.4
Description: Rabbit polyclonal CAS antibody (Tyr165)

CAS antibody (Tyr249)

70R-31500 100 ug
EUR 392.4
Description: Rabbit polyclonal CAS antibody (Tyr249)

CAS Polyclonal Antibody

40671-100ul 100ul
EUR 302.4

CAS Polyclonal Antibody

40671-50ul 50ul
EUR 224.4

p130 Cas Antibody

20-abx012761
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p130 Cas Antibody

ABF6350 100 ug
EUR 525.6

Anti-CAS Antibody

A04496 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CAS Antibody (CSE1L) detection.tested for IP, WB in Human.

Anti-CAS antibody

STJ92006 200 µl
EUR 236.4
Description: Rabbit polyclonal to CAS.

DiYO™-3 [equivalent to YO-YO®-3] *5 mM DMSO Solution* *CAS 156312-20-8*

17581 0.2 ml
EUR 262.8

TWO-PRO™ 1 [equivalent to TO-PRO®-1] *5 mM DMSO Solution* *CAS 157199-59-2*

17571 0.2 ml
EUR 262.8

TWO-PRO™ 3 [equivalent to TO-PRO®-3] *5 mM DMSO Solution* *CAS 157199-63-8*

17572 0.2 ml
EUR 262.8

LysoView 540, 1000X in DMSO

70061 50uL
EUR 246
Description: Minimum order quantity: 1 unit of 50uL

LysoView 540, 1000X in DMSO

70061-T 10uL
EUR 112.8
Description: Minimum order quantity: 1 unit of 10uL

LysoViewâ„¢ 405, 1000X in DMSO

70066 50uL
EUR 241.2
Description: Minimum order quantity: 1 unit of 50uL

LysoViewâ„¢ 488, 1000X in DMSO

70067 50uL
EUR 241.2
Description: Minimum order quantity: 1 unit of 50uL

MitoViewâ„¢ 720, 1000X in DMSO

70068 20X50UG
EUR 306
Description: Minimum order quantity: 1 unit of 20X50UG

RedDot 2, 200X in DMSO

40061 250uL
EUR 434.4
Description: Minimum order quantity: 1 unit of 250uL

RedDot 2, 200X in DMSO

40061-1 1mL
EUR 673.2
Description: Minimum order quantity: 1 unit of 1mL

RedDot 2, 200X in DMSO

40061-T 25uL
EUR 157.2
Description: Minimum order quantity: 1 unit of 25uL

Thiazole Orange, 10mM in DMSO

40077 1mL
EUR 174
Description: Minimum order quantity: 1 unit of 1mL

NucSpot 470, 1000X in DMSO

40083 200uL
EUR 446.4
Description: Minimum order quantity: 1 unit of 200uL

NucSpot 470, 1000X in DMSO

40083-T 20uL
EUR 127.2
Description: Minimum order quantity: 1 unit of 20uL

Thiazole Red, 1mM in DMSO

40087 1mL
EUR 384
Description: Minimum order quantity: 1 unit of 1mL

Oxazole Yellow, 1mM in DMSO

40089 1mL
EUR 403.2
Description: Minimum order quantity: 1 unit of 1mL

DMSO, labeling grade, 1 mL

15050 1 mL
EUR 44.4

Peelbl DMSO Resistant AdhFoil sh

PCR0542 PK100
EUR 265.62

DMSO Resistant Peel Seal Roll

PCR0852 1ROLL
EUR 1336.08

DMSO Resistant Peel Seal Roll

PCR0854 1ROLL
EUR 1470.6

DMSO Resistant Peel Seal Roll

PCR0856 1ROLL
EUR 19.87

DMSO Resistant Peel Seal Roll

PCR0858 1ROLL
EUR 318.06

DMSO Resistant Peel Seal Roll

PCR0860 1ROLL
EUR 1505.94

DMSO Resistant Peel Seal Roll

PCR0862 1ROLL
EUR 1656.42

DMSO Resistant Peel Seal Roll

PCR0864 1ROLL
EUR 19.28

p130 Cas Blocking Peptide

AF7826-BP 1mg
EUR 234

p130 Cas Blocking Peptide

AF7827-BP 1mg
EUR 234

p130 Cas Blocking Peptide

AF4748-BP 1mg
EUR 234

p130 Cas Blocking Peptide

AF6350-BP 1mg
EUR 234

CAS Polyclonal Conjugated Antibody

C40671 100ul
EUR 476.4

p130 Cas Polyclonal Antibody

ES3093-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p130 Cas Polyclonal Antibody

ES3093-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p130 Cas Polyclonal Antibody

ES3094-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p130 Cas Polyclonal Antibody

ES3094-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p130 Cas from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p130 Cas antibody (Tyr410)

70R-31035 100 ug
EUR 392.4
Description: Rabbit polyclonal p130 Cas antibody (Tyr410)

AE-1477 EzBlock CAS

2332617 3unit
EUR 352.8
Description: Casei n for wer st er n bl ot t i ng

p130 Cas (pY410) Antibody

abx010316-100ug 100 ug
EUR 526.8

p130 Cas (pT249) Antibody

20-abx009713
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p130 Cas Polyclonal Antibody

ABP52094-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165

p130 Cas Polyclonal Antibody

ABP52094-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165

p130 Cas Polyclonal Antibody

ABP52094-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y165

p130 Cas Polyclonal Antibody

ABP52095-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410

p130 Cas Polyclonal Antibody

ABP52095-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410

p130 Cas Polyclonal Antibody

ABP52095-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p130 Cas from Human, Mouse, Rat. This p130 Cas antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p130 Cas around the non-phosphorylation site of Y410

Anti-p130 Cas antibody

STJ94853 200 µl
EUR 236.4
Description: Rabbit polyclonal to p130 Cas.

Anti-p130 Cas antibody

STJ94854 200 µl
EUR 236.4
Description: Rabbit polyclonal to p130 Cas.

Donkey Anti-Sheep IgG, Salt Fractionation (Bulk)

30326-CAS-BLK 1g; bulk Ask for price

Drain Tap Assembly to suit baths with serial number: 75100

BAT7360 EACH
EUR 68.4

Kinesis Septa TCS 11mm Bought as part number without /S

CHR1750 EACH
EUR 2.28

Cycloheximide Solution (10% in DMSO Sterile)

C084-10x1ML 10x1 mL
EUR 232.8

Cycloheximide Solution (10% in DMSO Sterile)

C084-1ML 1 mL
EUR 64.8

TMRE, 2 mM solution in DMSO

70005 0.5ML
EUR 178.8
Description: Minimum order quantity: 1 unit of 0.5ML

6-TAMRA, SE in DMSO:100uL

90097 100uL
EUR 368.4
Description: Minimum order quantity: 1 unit of 100uL

6-Rox, SE in DMSO:(100uL)

90098 100uL
EUR 368.4
Description: Minimum order quantity: 1 unit of 100uL

EGTA AM *10 mM DMSO solution*

21006 1 mL
EUR 211.2

Ethidium homodimer I, 2mM DMSO solution

40014 0.5ML
EUR 308.4
Description: Minimum order quantity: 1 unit of 0.5ML

Ethidium homodimer III, 1mM in DMSO

40051 200uL
EUR 374.4
Description: Minimum order quantity: 1 unit of 200uL

Thiazole Red Homodimer, 1mM in DMSO

40080 200uL
EUR 426
Description: Minimum order quantity: 1 unit of 200uL

NucSpot Live 488, 1000X in DMSO

40081 50uL
EUR 426
Description: Minimum order quantity: 1 unit of 50uL

NucSpot Live 488, 1000X in DMSO

40081-T 10uL
EUR 139.2
Description: Minimum order quantity: 1 unit of 10uL

NucSpot Far-Red, 1000X in DMSO

40085 0.5mL
EUR 675.6
Description: Minimum order quantity: 1 unit of 0.5mL

NucSpot Far-Red, 1000X in DMSO

40085-T 50uL
EUR 157.2
Description: Minimum order quantity: 1 unit of 50uL

Thiazole Green, 10, 000X in DMSO

40086-0.5mL 0.5mL
EUR 225.6
Description: Minimum order quantity: 1 unit of 0.5mL

Thiazole Green, 10, 000X in DMSO

40086-1mL 1mL
EUR 344.4
Description: Minimum order quantity: 1 unit of 1mL

Thiazole orange *10 mM in DMSO*

17519 10 mL
EUR 138

Calcein AM, 4mm in anhydrous DMSO

80011-1 100uL
EUR 271.2
Description: Minimum order quantity: 1 unit of 100uL

DMSO Resistant Peel Seal 100 She

PCR0866 PK100
EUR 94.62

CYTO-13 *5 mM DMSO solution*

17553 0.5 mL
EUR 222

LAMP Green® *50X DMSO Solution*

17555 100 ul
EUR 301

Q4ever™ Green *1250X DMSO Solution*

17608 100 ul
EUR 151

Q4ever™ Green *1250X DMSO Solution*

17609 2 ml
EUR 2029

Phospho-p130 Cas (Tyr410) Antibody

AF3350 200ul
EUR 420

Phospho-p130 Cas (Tyr165) Antibody

AF4448 200ul
EUR 540

Phospho-p130 Cas (Tyr267) Antibody

AF7326 200ul
EUR 540

Phospho-p130 Cas (Tyr387) Antibody

AF7327 200ul
EUR 540

Phospho-p130 Cas (Tyr249) Antibody

AF2375 200ul
EUR 420

Statine *CAS 49642-07-1*

5109 100 mg
EUR 262.8

Coelenterazine *CAS#: 55779-48-1*

21150 250 ug
EUR 138

Coelenterazine *CAS#: 55779-48-1*

21156 1 mg
EUR 158.4

Coelenterazine *CAS#: 55779-48-1*

21166 10 mg
EUR 576

Zinquin *CAS#: 151606-29-0*

21260 5 mg
EUR 158.4
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